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The document examines the process and impact of an economic study in Uganda that found the cost of inaction on climate change to be 20–24 times higher than the cost of adaptation. This evidence facilitated the integration of climate change into national development plans (NDP II and NDP III), the elevation of the Climate Change Unit to a Department, and the passage of the National Climate Change Act 2021. Key success factors included continuous engagement with high-level leadership, an in-country presence, and the use of layered communication products like documentary films. However, challenges remain in sub-national implementation and the lack of dedicated climate budget lines in the national budgeting system.

The report argues that the cost of inaction regarding climate change in Uganda is significantly higher than the cost of adaptation, estimating annual losses between US$3.1 bn and 5.9 bn by 2025 compared to an adaptation cost of US$406 m over five years. It identifies critical vulnerabilities in water availability, agricultural exports (particularly coffee), biomass energy supply, and infrastructure resilience, while highlighting that many proposed adaptation measures are 'no regrets' investments that provide immediate development benefits.

The report finds that malaria cases in Tororo and Kabale are projected to more than double by 2050, driven primarily by population growth and secondarily by rising temperatures. Economic costs are expected to at least double, with Tororo's annual costs potentially rising to between US$20.1 million and US$560.5 million, and Kabale's to between US$1.55 million and US$41.7 million. While the evidence base for climate-malaria linkages in Uganda is limited, the study suggests that temperature increases will be particularly significant in the highland region of Kabale. Recommended adaptation strategies include strengthening disease surveillance, improving drainage in infrastructure projects, and continuing the distribution of long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS), both of which are identified as cost-effective interventions.

The document examines the intersection of climate change, population growth, and malaria in Uganda's Tororo and Kabale districts. It projects that the economic costs of malaria in these areas could more than double by 2050, driven by rising temperatures and increased population exposure. The study emphasizes the need for district-specific adaptation strategies, such as Long Lasting Insecticide Nets (LLINs) and Indoor Residential Spraying (IRS), and calls for improved climate-malaria research and cross-ministerial collaboration to maximize health co-benefits.