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The report estimates that making Uganda's infrastructure climate-resilient will cost between US$52-66 million annually by 2020, rising to US$638-1,157 million by 2050. Residential buildings are the most affected sector, accounting for approximately half of all adaptation costs. The study also projects that annual damages from extreme events, if frequency doubles every 25 years, could reach US$738-3,294 million by 2050. Key adaptation priorities include climate-proofing public buildings and developing resilient transport standards.

The case study examines the Trans-Harmony Farms project by the Initiative of Trans with A Mission (ITWAM) in the Mbale and Manafwa districts of Uganda. It details how the initiative supports 29 LGBTQIA+ farmers by providing training in permaculture and agroforestry, creating a cooperative to bypass systemic exclusion from government resources, and developing a digital app to ensure safe market access. The document analyzes these efforts through five dimensions of transformative potential: alignment with local contexts, resource enablement, relationship building, challenging power structures, and supporting systems learning. It highlights the critical role of the 2023 Anti-Homosexuality Act (AHA) in exacerbating the marginalization of these farmers and the strategic use of trusted personal relationships with local government officials to navigate a hostile legal environment.