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The agreement between LA Referencia and the Inter-American Institute for Global Change Research (IAI) focuses on strengthening open science capacities in Latin America and the Caribbean. The partnership aims to align IAI's 2024–2030 Strategic Plan—which includes developing a digital infrastructure for open data by 2026—with LA Referencia's existing digital infrastructure for scientific publications. Key areas of cooperation include joint capacity-building programs, collaborative funding proposals, and improved regional communication mechanisms.

The agreement formalizes the status of the Instituto Humboldt as an Associate of the IAI, focusing on the exchange of scientific data, joint project development, and capacity building in transdisciplinary research and science diplomacy to address climate change and biodiversity loss.

The IAI and CLARA have entered into a non-binding agreement to promote regional scientific capacities through the use of advanced networks, focusing on data management, open publications, and technological infrastructure for global change research in Latin America.

The 1992 agreement creates the Inter-American Institute for Global Change Research (IAI) to address insufficient scientific knowledge of the Earth system and the impacts of global change. The IAI is structured as a regional network of cooperating entities with a specific scientific agenda focusing on tropical ecosystems, biodiversity, and climate variability. It is governed by a Conference of the Parties, an Executive Council, a Scientific Advisory Committee, and an Executive Directorate. The agreement outlines the criteria for establishing Research Centers, the role of affiliated institutions and associates, and a funding model based on voluntary contributions from member states and external partners.

A 1998 Statement of Intent between the United States and Chile to launch the Pan-American Climate Information System for Disaster Preparedness (PACIS) to reduce disasters and improve decision-making regarding climate fluctuations.

A joint declaration from the European Commission and the African Union Commission following their fourth College-to-College meeting on 1 October 2008 in Brussels. The document outlines agreements to implement the Africa-EU Strategic Partnership across eight thematic areas, including security, governance, economic integration, health, energy, climate change, migration, and science and technology.