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The report evaluates the hydrological impact of climate change on the Lake Bunyonyi catchment within the Ruhezamyenda catchment in southwestern Uganda. Using the COSERO hydrological model and CMIP5 global climate model ensembles under RCP4.5 and RCP8.5 scenarios, the study projects increases in temperature, precipitation, and evapotranspiration for the mid-term (20412070) and far future (20712100). While runoff trends show significant uncertainty, there is a general trend toward increasing runoff, particularly in the far future under RCP8.5. The report identifies 'no-regrets' adaptation options focusing on governance, land management, and data collection to address risks such as soil erosion, landslides, and wetland degradation.