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The Cuando River Basin is a largely pristine transboundary system traversing Angola, Zambia, Namibia, and Botswana. It is characterized by a unique hydrological system where water from the Angolan highlands flows through extensive floodplains, occasionally connecting with the Okavango and Zambezi basins. The region is a critical wildlife corridor within the KAZA TFCA, supporting significant populations of elephants and lions, though it faces threats from poaching, uncontrolled fires, and climate change. Human populations are sparse and primarily rely on subsistence agriculture and the harvesting of natural products, with a growing trend toward urban migration due to the basin's exceptionally poor soil fertility.