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The Threatened or Protected Species Regulations, 2007, issued under the National Environmental Management: Biodiversity Act 10 of 2004, establish a comprehensive legal framework for managing restricted activities involving listed threatened and protected species in South Africa. The regulations detail a permit system for activities such as hunting, breeding, and trade, and mandate the registration of facilities including captive breeding operations, game farms, and sanctuaries. It includes strict prohibitions on certain hunting methods and activities involving large predators and rhinoceros species, while providing mechanisms for risk assessments, appeals, and the establishment of a Scientific Authority.