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The paper examines interactions between six specific SDGs (1, 2, 3, 5, 9, and 14) using a seven-point scale to categorize relationships as reinforcing, enabling, or constraining. It finds that positive interactions generally outweigh negative ones, particularly for gender equality, which acts as a lever for multiple other goals. However, it highlights significant institutional barriers to integrated implementation, as most governments operate through sectoral ministries that lack joint agendas. The author argues for the creation of an international open knowledge platform to systematize SDG interaction analysis and suggests that 'mission-oriented innovation' and strategic foresight mechanisms can help overcome short-termism in infrastructure and industrial policy.