Report II

The document outlines concerns that the CaMV promoter used in genetically modified organisms could lead to the creation of new infectious viruses, increase susceptibility across species including humans due to the removal of the viral coating, and cause cancer through gene overactivity. It highlights the risk of horizontal gene transfer and gene instability, concluding with the authors' recommendation that all products containing the CaMV promoter be withdrawn.

• The use of the CaMV promoter in genetic engineering may allow elements of the promoter to combine with dormant viruses in host plants, potentially creating new infectious viruses, with specific concerns noted regarding the similarity of CaMV to viruses such as hepatitis B.
• The removal of the natural viral coating during genetic engineering may make all species, including humans and animals, susceptible to infection, whereas the natural CaMV virus only infects a limited range of plants.
• The strength of the CaMV promoter could lead to the continuous overactivity of genes, which may result in cancer, and the promoter's 'recombination hotspot' may increase the instability of inserted transgenes.
• The properties of the promoter facilitate the mobilization of genes from the host into the environment via horizontal gene transfer, which could lead to large-scale and unpredictable gene rearrangements.
• Based on these hazards, the authors argue that all products and crops that contain the CaMV promoter should be withdrawn.

APA

Scientists for Global Responsibility (2002). Report II. https://www.sgr.org.uk/resources/chardon-report-ii-hazards-arising-use-camv-promoter-genetic-engineering

Chicago

Scientists for Global Responsibility. Report II. 2002. https://www.sgr.org.uk/resources/chardon-report-ii-hazards-arising-use-camv-promoter-genetic-engineering.

Wikipedia

{{cite report |author=Scientists for Global Responsibility |title=Report II |date=May 2002 |url=https://www.sgr.org.uk/resources/chardon-report-ii-hazards-arising-use-camv-promoter-genetic-engineering |access-date=23 October 2026 |via=Climate Insights Directory}}

BibTeX

@techreport{scientistsforglobalresponsibility2002report, author = {{Scientists for Global Responsibility}}, title = {{Report II}}, institution = {Scientists for Global Responsibility}, year = {2002}, month = may, url = {https://www.sgr.org.uk/resources/chardon-report-ii-hazards-arising-use-camv-promoter-genetic-engineering}, urldate = {2026-10-23}, note = {Indexed by Climate Insights Directory} }