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The Stockholm Environment Institute (SEI) has launched an initiative to investigate the cross-sector links between water, energy, and food (the WEF nexus) to support sustainable resource management. The initiative employs a 'nexus toolkit' combining the Water Evaluation and Planning (WEAP) system and the Long-range Energy Alternatives Planning (LEAP) system to provide quantitative assessments and scenario modeling. The program is structured around three themes—governing, understanding, and implementing the nexus—and is being applied through case studies in Myanmar, Zambia, and Colombia to help decision-makers align sector policies and manage resource trade-offs.