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The document argues that mancozeb and its metabolite ethylene thiourea (ETU) pose unacceptable risks to human health and the environment, citing a 2021 European Union ban and deficiencies in Canada's regulatory oversight. The requesters claim the PMRA has failed to implement its own 2020 risk mitigation measures, ignored critical biomonitoring data showing widespread ETU exposure in Canadians, and relied on outdated US water monitoring data to underestimate cancer risks. They specifically highlight risks of endocrine disruption, reproductive toxicity, and harm to non-target arthropods, birds, and aquatic organisms, demanding a special review and the suspension of product renewals.

Civil society organisations are calling on the German government to support the classification of Resorcinol as a substance of very high concern (SVHC) under the REACH regulation. They argue that Resorcinol is a known endocrine disruptor that inhibits thyroperoxidase (TPO), affecting thyroid hormone levels essential for brain development, particularly in unborn children. The authors highlight that Resorcinol is a high-volume compound used in cosmetics, pharmaceuticals, and rubber products, leading to significant exposure for workers and the public. They contend that the substance meets the 'equivalent level of concern' (ELoC) criteria due to the irreversible nature of its developmental effects, such as hypothyroidism and neurological impacts.

The document argues that Resorcinol should be identified as a substance of very high concern (SVHC) under REACH article 57(f) because it is an endocrine disruptor that inhibits thyroperoxidase (TPO), affecting thyroid hormone levels. The authors highlight severe developmental risks for unborn children, including hypothyroidism and neurological impacts, and note that the substance is a high-volume compound used in cosmetics, pharmaceuticals, and rubber products. They contend that the substance meets the 'equivalent level of concern' (ELoC) criteria and that failure to identify it would undermine the EU Chemicals Strategy for Sustainability.